Changes in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and E
- 1 Qilu Medical University, China
Abstract
This study aims to elucidate the influence of supplementation with different doses of Vitamin C (VC) and Vitamin E (VE) on Prothrombin Time (PT) in mice; forty eight mice are randomly divided into six treatment groups, which are fed different dose VC and VE except for control Check (CK) for eight weeks. Blood samples are obtained from the mouse canthus to measure PT and platelet parameters. Administration of different doses of VC and VE to mice cause coagulation function damage.
DOI: https://doi.org/10.3844/ajbbsp.2020.170.176
Copyright: © 2020 Hongwei Li, Jing Cheng, Wei Wang, Xiangcui Chen, Tongbing Qi, Xinzhuo Tu, Jing Zhang, Weitong Cui and Qinglu Wang. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Vitamin C
- Vitamin E
- Prothrombin Time
- Platelet Parameters