TY - JOUR AU - Li, Hongwei AU - Cheng, Jing AU - Wang, Wei AU - Chen, Xiangcui AU - Qi, Tongbing AU - Tu, Xinzhuo AU - Zhang, Jing AU - Cui, Weitong AU - Wang, Qinglu PY - 2020 TI - Changes in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and E JF - American Journal of Biochemistry and Biotechnology VL - 16 IS - 2 DO - 10.3844/ajbbsp.2020.170.176 UR - https://thescipub.com/abstract/ajbbsp.2020.170.176 AB - This study aims to elucidate the influence of supplementation with different doses of Vitamin C (VC) and Vitamin E (VE) on Prothrombin Time (PT) in mice; forty eight mice are randomly divided into six treatment groups, which are fed different dose VC and VE except for control Check (CK) for eight weeks. Blood samples are obtained from the mouse canthus to measure PT and platelet parameters. Administration of different doses of VC and VE to mice cause coagulation function damage.