Research Article Open Access

Molecular Docking of New Active Compounds Towards the Acetylcholinesterase Enzyme

Lemaoui Tarek1, Hammoudi Nour El Houda1, Benguerba Yacine1 and Attoui Ayoub1
  • 1 Université Ferhat ABBAS Sétif-1, Algeria

Abstract

Molecular docking is a key instrument in structural molecular biology and computer-assisted drug design. The objective of ligand-protein docking is to expect the main binding mode(s) of a ligand with a protein of known three-dimensional structure. Effective docking methods search high-dimensional spaces effectively and finding a scoring function that correctly ranks candidate dockings (Morris et al., 2008). In this study molecular docking study was performed for 54 Acetylcholinesterase Inhibitors compounds.

Current Research in Bioinformatics
Volume 8 No. 1, 2019, 18-20

DOI: https://doi.org/10.3844/ajbsp.2019.18.20

Submitted On: 25 December 2019 Published On: 27 February 2020

How to Cite: Tarek, L., El Houda, H. N., Yacine, B. & Ayoub, A. (2019). Molecular Docking of New Active Compounds Towards the Acetylcholinesterase Enzyme. Current Research in Bioinformatics, 8(1), 18-20. https://doi.org/10.3844/ajbsp.2019.18.20

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Keywords

  • Docking
  • Acetylcholinesterase Enzyme
  • Molecular Modeling