TY  - JOUR
AU  - Hasan, Ahmed Flayyih 
AU  - Alankooshi, Azhar Azher 
AU  - Abbood, Alaa Saadi 
AU  - Dulimi, Ali Ghazi 
AU  - Mohammed Al-Khuzaay, Hiba 
AU  - Elsaedy, Eslam Ahmed 
AU  - Tousson, Ehab 
PY  - 2023
TI  - Impact of B-Glucan Against Ehrlich Ascites Carcinoma Induced Renal Toxicity in Mice
JF  - OnLine Journal of Biological Sciences
VL  - 23
IS  - 1
DO  - 10.3844/ojbsci.2023.103.108
UR  - https://thescipub.com/abstract/ojbsci.2023.103.108
AB  - Several studies have been focused on identifying alternative medicines for the treatment of cancer. This study aimed to investigate the impact of B-Glucans extract (BG) against Ehrlich Ascites Carcinoma (EAC) induced toxicity and tissue damage in kidney. A total of 40 mice were assigned randomly to four groups (G1, control; G2, B-Glucans (75 mg/kg bw/day) orally for 2 weeks; G3, EAC and G4, EAC + BG). Current results revealed, EAC induced significant elevation in urea, creatinine, potassium (k+), chloride (Cl-) ions, kidney injury and significant decrease in sodium (Na+) and calcium (Ca++) ions when compared to B-glucans and control groups. Conversely, EAC + B-glucans modulate these changes and improved the renal functions and structure. EAC induced renal dysfunction and B-Glucans has the ability to improve renal functions. We can conclude that; BG could be used as an adjuvant therapy for kidney in ascites of hepatocellular carcinoma, Schistosoma and hepatitis.