@article {10.3844/ojbsci.2023.103.108,
article_type = {journal},
title = {Impact of B-Glucan Against Ehrlich Ascites Carcinoma Induced Renal Toxicity in Mice},
author = {Hasan, Ahmed Flayyih and Alankooshi, Azhar Azher and Abbood, Alaa Saadi and Dulimi, Ali Ghazi and Mohammed Al-Khuzaay, Hiba and Elsaedy, Eslam Ahmed and Tousson, Ehab},
volume = {23},
number = {1},
year = {2023},
month = {Feb},
pages = {103-108},
doi = {10.3844/ojbsci.2023.103.108},
url = {https://thescipub.com/abstract/ojbsci.2023.103.108},
abstract = {Several studies have been focused on identifying alternative medicines for the treatment of cancer. This study aimed to investigate the impact of B-Glucans extract (BG) against Ehrlich Ascites Carcinoma (EAC) induced toxicity and tissue damage in kidney. A total of 40 mice were assigned randomly to four groups (G1, control; G2, B-Glucans (75 mg/kg bw/day) orally for 2 weeks; G3, EAC and G4, EAC + BG). Current results revealed, EAC induced significant elevation in urea, creatinine, potassium (k+), chloride (Cl-) ions, kidney injury and significant decrease in sodium (Na+) and calcium (Ca++) ions when compared to B-glucans and control groups. Conversely, EAC + B-glucans modulate these changes and improved the renal functions and structure. EAC induced renal dysfunction and B-Glucans has the ability to improve renal functions. We can conclude that; BG could be used as an adjuvant therapy for kidney in ascites of hepatocellular carcinoma, Schistosoma and hepatitis.},
journal = {OnLine Journal of Biological Sciences},
publisher = {Science Publications}
}