@article {10.3844/amjnsp.2015.8.12, article_type = {journal}, title = {Assessment of Quality of Life, Anxiety and Depression in Children with Turner Syndrome: A Case-Control Study}, author = {Saad, Khaled and Al-Atram, Abdulrahman Abdullah and Abdel Baseer, Khaled A. and Ali, Ahmed M. and El-Houfey, Amira A.}, volume = {6}, year = {2015}, month = {Mar}, pages = {8-12}, doi = {10.3844/amjnsp.2015.8.12}, url = {https://thescipub.com/abstract/amjnsp.2015.8.12}, abstract = {Turner syndrome is a genetic disorder that affects only females and is caused by the loss of the whole or a part of the X-chromosome. The aim of this study was to assess the quality of life and frequency of anxiety and depression in a cohort of Egyptian children with Turner Syndrome (TS) diagnosed in Assiut university hospitals, Assiut, Egypt. In a case-control study; 40 females with Turner Syndrome (TS), aged 6-16 years, diagnosed in Assiut university hospitals, Upper Egypt, were compared to 40 age- matched apparent healthy girls as controls. They were subjected to full history taking, thorough clinical examination and assessment of pediatric quality of life; we used pediatric anxiety and depression scores. For cognitive assessment, Health-Related Quality of Life (HR-QOL) and psychological evaluation of anxiety and depression; we used the “Children Depression Scale” (CDI), “Children Anxiety Scale” Wechsler Intelligence Scale for Children (WISC) and SF-36 by trained psychiatrists blind to the study. Our study revealed Children Anxiety Scale scores ranged from 13-41 for patients with TS and 5-23 for controls. The mean anxiety scores were significantly higher in TS patients as compared to controls (p}, journal = {Neuroscience International}, publisher = {Science Publications} }