TY  - JOUR
AU  - Taherianfard, M. 
AU  - Bahaodini, A. 
AU  - Fazeli, M. 
AU  - Haghighi, S. Karimi 
PY  - 2014
TI  - Interaction of γ Aminobutyric Acid B Receptors and Electromagnetic Field in the Fear Response
JF  - Neuroscience International
VL  - 4
IS  - 2
DO  - 10.3844/amjnsp.2013.56.59
UR  - https://thescipub.com/abstract/amjnsp.2013.56.59
AB  - One of the most neurotransmission system consistently linked with fear response is GABAergic system. GABA through GABAB receptor can influence fear response. The aim of the present investigation was to examine the effect of IP injection of baclofen (GABAB agonist) and CGP35348 (GABAB antagonist) along with EMF exposure on frequency of fear response. Fifty adult male rats weighing 180-200 g were used. Animals were divided in ten groups, of which five groups were exposed to ELF-EMF for 30 days at 8 h day-1 in a solenoid, creating an electromagnetic field of 500 µT by a 50 Hz electrical current. Animals were then treated with various doses of baclofen and CGP35348 before being exposed to electrical shock. Each animal were received 100 electrical shocks every session. After shock induction, the fear response was determined by monitoring the reaction of shocked animals to a normal rat which was placed in the electroshock chamber. Data was analyzed by Mann-Whitney test. Significant level was considered to be p