@article {10.3844/ajidsp.2024.11.23, article_type = {journal}, title = { Analysis of the Clinical Incidence and Correlation between Colorectal Cancer and Microorganisms }, author = {Koutouvalis, Kalia and Bejarano, Pablo Augusto}, volume = {20}, number = {1}, year = {2024}, month = {Jun}, pages = {11-23}, doi = {10.3844/ajidsp.2024.11.23}, url = {https://thescipub.com/abstract/ajidsp.2024.11.23}, abstract = {In this single institution retrospective medical record review, patients diagnosed with colorectal cancer from the years 2018-2022 were evaluated to distinguish an associative linear relationship between diagnosed colorectal cancer and a positive result for the presence of an infectious microorganism. A total of 241 patients diagnosed with colorectal cancer accompanied by a test or order placed with the purpose of ruling out or identifying a microorganism were compiled. The data were analyzed on a linear model to determine association between the two variables and to further investigate trends associated with the presence of a dominant microorganism and the characteristics of the colorectal cancer. Based on the observed clinical incidence, the greatest presence of a dominant infectious microorganism occurred in patients with left sided colon cancers. Species evaluation within this cohort found similarity to microorganisms identified as common post-treatment infectious pathogens including Escherichia coli, Enterococcus faecalis and Streptococcus species. The apparent trend of a dominant microorganism within left sided colorectal cancers suggests clinical relevance when considering further treatment and management of infections within this population.}, journal = {American Journal of Infectious Diseases}, publisher = {Science Publications} }