TY  - JOUR
AU  - Vaghari, Hamideh 
AU  - Eskandari, Maryam 
AU  - Sobhani, Vahideh 
AU  - Berenjian, Aydin 
AU  - Song, Yuanda 
AU  - Jafarizadeh-Malmiri, Hoda 
PY  - 2015
TI  - Process Intensification for Production and Recovery of Biological Products
JF  - American Journal of Biochemistry and Biotechnology
VL  - 11
IS  - 1
DO  - 10.3844/ajbbsp.2015.37.43
UR  - https://thescipub.com/abstract/ajbbsp.2015.37.43
AB  - Bioprocesses are important biological reactions which need several sophisticated methods and equipment to produce many novel and important compounds which some of them are traditionally produced by synthetic chemical reactions. In bioprocesses, the products are often produced in a dilute environment and finally they require a high purity. Because of that, downstream processes are usually included a large number of separation steps. Size and capital costs of the equipment are two main limitations of using bioprocesses at industrial scale. Bioprocess intensification by minimizing, substitution, moderation and simplification of the methods and equipment, drastically leads to sustainable processes. This study looks at intensification of the emerging equipment and operational methods and their advantages to lead smaller and cleaner bioprocess plants which in turn, increases production efficiency and quality and decreases byproducts formation, capital cost and energy consumption.