@article {10.3844/ajbbsp.2015.176.181,
article_type = {journal},
title = {Gene Transfer Vector Derived from Jembrana Disease Virus: A Review},
author = {Kusumawati, Asmarani and Wanahari, Tenri A. and Astuti, Pudji and Mappakaya, Basofi A. and Wasito,},
volume = {11},
number = {3},
year = {2015},
month = {Sep},
pages = {176-181},
doi = {10.3844/ajbbsp.2015.176.181},
url = {https://thescipub.com/abstract/ajbbsp.2015.176.181},
abstract = {The etiological agent of Jembrana disease is a virus which was accordingly named Jembrana Disease Virus (JDV). JDV was a member of the family of Retroviridae, of the subfamily of lentiviruses. As a member of the lentivirus, JDV has general property to integrate their genome into the chromosomal DNA of the host-cells. It is one of their common properties which is not shared by simple retroviruses such as murine leukimia virus or avian sarcoma virus. Lentiviruses are highly species-specific and share the property of replicating in dividing and non-dividing terminally differentiated cells. JDV-based gene transfer vector which had been developed is appeared to possess a broad tropism and a unique capacity of mediating efficient gene transfer. This review summarize JDV-based viral vector system that has been developed. The main principles and components of JDV viral gene transfer system and its implication in the future research will be discussed.},
journal = {American Journal of Biochemistry and Biotechnology},
publisher = {Science Publications}
}